Piscine birnavirus triggers antiviral immune response in trout red blood cells, despite not being infective

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Piscine birnavirus triggers antiviral immune response in trout red blood cells, despite not being infective.

Background: Some fish viruses, such as piscine orthoreovirus and infectious salmon anemia virus, target red blood cells (RBCs), highly replicate inside them and induce an immune response. However, the implications of RBCs in the context of birnavirus infection (i.e, infectious pancreatic necrosis virus (IPNV)) have not yet been studied. Methods:Ex vivo trout RBCs were obtained from peripheral b...

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Piscine birnavirus triggers antiviral immune response in trout

Some fish viruses, such as piscine orthoreovirus and infectious Background: salmon anemia virus, target red blood cells (RBCs), highly replicate inside them and induce an immune response. However, the implications of RBCs in the context of birnavirus infection (i.e, infectious pancreatic necrosis virus (IPNV)) have not yet been studied. trout RBCs were obtained from peripheral blood, ficoll Met...

متن کامل

Piscine birnavirus triggers antiviral immune response in trout

Some fish viruses, such as piscine orthoreovirus and infectious Background: salmon anemia virus, target red blood cells (RBCs), highly replicate inside them and induce an immune response. However, the implications of RBCs in the context of birnavirus infection (i.e, infectious pancreatic necrosis virus (IPNV)) have not yet been studied. trout RBCs were obtained from peripheral blood, ficoll Met...

متن کامل

Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective

Some fish viruses, such as piscine orthoreovirus and infectious Background salmon anemia virus, target red blood cells (RBCs), replicate inside them and induce an immune response. However, the roles of RBCs in the context of infectious pancreatic necrosis virus (IPNV) infection have not been studied yet. : Ex vivo rainbow trout RBCs were obtained from peripheral blood, Methods Ficoll purified ...

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TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response.

Langerhans cells (LC) are a unique subset of dendritic cells (DC), present in the epidermis and serving as the first line of defense against pathogens invading the skin. To investigate the role of human LCs in innate immune responses, we examined TLR expression and function of LC-like DCs derived from CD34+ progenitor cells and compared them to DCs derived from peripheral blood monocytes (monoc...

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ژورنال

عنوان ژورنال: F1000Research

سال: 2017

ISSN: 2046-1402

DOI: 10.12688/f1000research.12994.1